Glutathione depletion in chronic lymphocytic leukemia B lymphocytes
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چکیده
منابع مشابه
Glutathione depletion in chronic lymphocytic leukemia B lymphocytes.
Glutathione (GSH) content may be the major determinant of a cell's sensitivity to cytotoxic alkylating agents. In the present study, the GSH concentration was determined in lymphocytes isolated from the blood of normal subjects and patients with chronic lymphocytic leukemia (CLL). Comparable levels were found in both types of cells. Incubation for 20 hours led to a decrease in GSH to 51% of bas...
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ژورنال
عنوان ژورنال: Blood
سال: 1992
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v80.8.2038.bloodjournal8082038